Terminal PEGylated DNA–Gold Nanoparticle Conjugates Offering High Resistance to Nuclease Degradation and Efficient Intracellular Delivery of DNA Binding Agents

[Image: see text] Over the past 10 years, polyvalent DNA–gold nanoparticle (DNA–GNP) conjugate has been demonstrated as an efficient, universal nanocarrier for drug and gene delivery with high uptake by over 50 different types of primary and cancer cell lines. A barrier limiting its in vivo effectiv...

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Detalles Bibliográficos
Autores principales: Song, Lei, Guo, Yuan, Roebuck, Deborah, Chen, Chun, Yang, Min, Yang, Zhongqiang, Sreedharan, Sreejesh, Glover, Caroline, Thomas, Jim A., Liu, Dongsheng, Guo, Shengrong, Chen, Rongjun, Zhou, Dejian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554298/
https://www.ncbi.nlm.nih.gov/pubmed/26237203
http://dx.doi.org/10.1021/acsami.5b05228

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