Sublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model

BACKGROUND: Glioblastoma is a highly lethal neoplasm that frequently recurs locally after radiotherapy, and most of these recurrences originate from near the irradiated target field. In the present study, we identified the effects of radiation on glioma invasion and p53, TIMP-2, and MMP-2 expression...

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Detalles Bibliográficos
Autores principales: Pei, Jian, Park, In-Ho, Ryu, Hyang-Hwa, Li, Song-Yuan, Li, Chun-Hao, Lim, Sa-Hoe, Wen, Min, Jang, Woo-Youl, Jung, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554349/
https://www.ncbi.nlm.nih.gov/pubmed/26245666
http://dx.doi.org/10.1186/s13014-015-0475-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554349/
https://www.ncbi.nlm.nih.gov/pubmed/26245666
http://dx.doi.org/10.1186/s13014-015-0475-8

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