Specific Inhibition of β-Catenin in Jeko-1 Mantle Cell Lymphoma Cell Line Decreases Proliferation and Induces Apoptosis

BACKGROUND: The canonical Wnt signaling pathway has been considered as a potent oncogenic signaling in the initiation and progression of hematological malignancies. As a key regulator of the Wnt signaling pathway, the role of β-catenin in mantle cell lymphoma (MCL) pathogenesis and progression was i...

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Detalles Bibliográficos
Autores principales: He, Jinshui, Huang, Yiqun, Weng, Jianmin, Xiao, Liyun, Weng, Kaizhi, Ma, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554364/
https://www.ncbi.nlm.nih.gov/pubmed/26227550
http://dx.doi.org/10.12659/MSM.893514

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