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Influence of hypoxia and irradiation on osteopontin expression in head and neck cancer and glioblastoma cell lines

BACKGROUND: Tumor hypoxia is a known risk factor for reduced response to radiotherapy. The evaluation of noninvasive methods for the detection of hypoxia is therefore of interest. Osteopontin (OPN) has been discussed as an endogenous hypoxia biomarker. It is overexpressed in many cancers and is invo...

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Detalles Bibliográficos
Autores principales:	Wohlleben, Gisela, Scherzad, Agmal, Güttler, Antje, Vordermark, Dirk, Kuger, Sebastian, Flentje, Michael, Polat, Buelent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554368/ https://www.ncbi.nlm.nih.gov/pubmed/26259597 http://dx.doi.org/10.1186/s13014-015-0473-x

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