Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier

To clarify the significance of immunoglobulin G autoantibody specific for the astrocyte water channel aquaporin-4 in cerebrospinal fluid, aquaporin-4-immunoglobulin G from a neuromyelitis optica patient was administered intrathecally to naïve mice, and the distribution and pathogenic impact was eval...

Descripción completa

Detalles Bibliográficos
Autores principales: Asgari, Nasrin, Berg, Carsten Tue, Mørch, Marlene Thorsen, Khorooshi, Reza, Owens, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554446/
https://www.ncbi.nlm.nih.gov/pubmed/26339679
http://dx.doi.org/10.1002/acn3.221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554446/
https://www.ncbi.nlm.nih.gov/pubmed/26339679
http://dx.doi.org/10.1002/acn3.221

Ejemplares similares