Cargando…

Characterization of the l-alanine exporter AlaE of Escherichia coli and its potential role in protecting cells from a toxic-level accumulation of l-alanine and its derivatives

We previously reported that the alaE gene of Escherichia coli encodes the l-alanine exporter AlaE. The objective of this study was to elucidate the mechanism of the AlaE exporter. The minimum inhibitory concentration of l-alanine and l-alanyl-l-alanine in alaE-deficient l-alanine-nonmetabolizing cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Seryoung, Ihara, Kohei, Katsube, Satoshi, Hori, Hatsuhiro, Ando, Tasuke, Isogai, Emiko, Yoneyama, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554458/ https://www.ncbi.nlm.nih.gov/pubmed/26073055 http://dx.doi.org/10.1002/mbo3.269

Ejemplares similares

l-Alanine Exporter AlaE Functions as One of the d-Alanine Exporters in Escherichia coli
por: Katsube, Satoshi, et al.
Publicado: (2023)

L-Alanine Exporter, AlaE, of Escherichia coli Functions as a Safety Valve to Enhance Survival under Feast Conditions
por: Katsube, Satoshi, et al.
Publicado: (2019)

L-Alanine Prototrophic Suppressors Emerge from L-Alanine Auxotroph through Stress-Induced Mutagenesis in Escherichia coli
por: Mishima, Harutaka, et al.
Publicado: (2021)

Conformational transition induced in the aspartate:alanine antiporter by l-Ala binding
por: Suzuki, Satomi, et al.
Publicado: (2022)

l-Alanine hydrochloride monohydrate
por: Yamada, Kazuhiko, et al.
Publicado: (2008)

Uptake of l-Alanine and Its Distinct Roles in the Bioenergetics of Trypanosoma cruzi
por: Girard, Richard M. B. M., et al.
Publicado: (2018)

Alanine dehydrogenases from four different microorganisms: characterization and their application in L-alanine production
por: Gu, Pengfei, et al.
Publicado: (2023)

Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma
por: Guo, Min, et al.
Publicado: (2009)

Production of β-methylamino-L-alanine (BMAA) and Its Isomers by Freshwater Diatoms
por: Violi, Jake P., et al.
Publicado: (2019)

Metabolic engineering of microorganisms for L-alanine production
por: Liu, Pingping, et al.
Publicado: (2021)

Identification and expression analyses of the alanine aminotransferase (AlaAT) gene family in poplar seedlings
por: Xu, Zhiru, et al.
Publicado: (2017)

N-Cinnamoyl-l-phenylalanine methyl ester
por: Bornaghi, Laurent F., et al.
Publicado: (2007)

l-Alanine methyl ester hydrochloride monohydrate
por: Lutz, Martin, et al.
Publicado: (2011)

How the Neurotoxin β-N-Methylamino-l-Alanine Accumulates in Bivalves: Distribution of the Different Accumulation Fractions among Organs
por: Lepoutre, Alexandra, et al.
Publicado: (2020)

Antimicrobial activity of tea catechin against canine oral bacteria and the functional mechanisms
por: BAI, Lanlan, et al.
Publicado: (2016)

Role of L-alanine for redox self-sufficient amination of alcohols
por: Klatte, Stephanie, et al.
Publicado: (2015)

Gliotoxicity of the cyanotoxin, β-methyl-amino-(L)-alanine (BMAA)
por: Chiu, Alexander S., et al.
Publicado: (2013)

Equilibrium Dynamics of β-N-Methylamino-L-Alanine (BMAA) and Its Carbamate Adducts at Physiological Conditions
por: Zimmerman, David, et al.
Publicado: (2016)

Correction for Girard et al., “Uptake of l-Alanine and Its Distinct Roles in the Bioenergetics of Trypanosoma cruzi”
por: Girard, Richard M. B. M., et al.
Publicado: (2018)

Biochemical characterization of specific Alanine Decarboxylase (AlaDC) and its ancestral enzyme Serine Decarboxylase (SDC) in tea plants (Camellia sinensis)
por: Bai, Peixian, et al.
Publicado: (2021)

The Sodium-Alanine Interaction in Rabbit Ileum : Effect of alanine on sodium fluxes
por: Curran, Peter F., et al.
Publicado: (1970)

The Sodium-Alanine Interaction in Rabbit Ileum : Effect of sodium on alanine fluxes
por: Hajjar, Jean Jacques, et al.
Publicado: (1970)

Correction: The mechanism of β-N-methylamino-L-alanine inhibition of tRNA aminoacylation and its impact on misincorporation
por: Han, Nien-Ching, et al.
Publicado: (2022)

A Novel Synthetic Approach to C-Glycosyl-d- and l-Alanines
por: Martinková, Miroslava, et al.
Publicado: (2008)

Optimization of a reduced enzymatic reaction cascade for the production of L-alanine
por: Gmelch, Tobias J., et al.
Publicado: (2019)

β-N-Methylamino-l-alanine (BMAA) perturbs alanine, aspartate and glutamate metabolism pathways in human neuroblastoma cells as determined by metabolic profiling
por: Engskog, Mikael K. R., et al.
Publicado: (2017)

N-Acryloylphenylalanine
por: Wu, Cong-Ren, et al.
Publicado: (2008)

Heat Capacities of N-Acetyl Amides of Glycine, L-Alanine, L-Valine, L-Isoleucine, and L-Leucine
por: Štejfa, Vojtěch, et al.
Publicado: (2023)

Prolonged continuous intravenous infusion of the dipeptide L-alanine- L-glutamine significantly increases plasma glutamine and alanine without elevating brain glutamate in patients with severe traumatic brain injury
por: Nägeli, Mirjam, et al.
Publicado: (2014)

A Direct Analysis of β-N-methylamino-l-alanine Enantiomers and Isomers and Its Application to Cyanobacteria and Marine Mollusks
por: Metcalf, James S., et al.
Publicado: (2023)

Reconfiguration of N Metabolism upon Hypoxia Stress and Recovery: Roles of Alanine Aminotransferase (AlaAT) and Glutamate Dehydrogenase (GDH)
por: Diab, Houssein, et al.
Publicado: (2016)

Reinterpreting the Mechanism of Inhibition of Mycobacterium tuberculosisd-Alanine:d-Alanine Ligase by d-Cycloserine
por: Prosser, Gareth A., et al.
Publicado: (2013)

Cyanobacterial Neurotoxin β-N-Methylamino-L-alanine (BMAA) in Shark Fins
por: Mondo, Kiyo, et al.
Publicado: (2012)

Role of the gerA operon in L-alanine germination of Bacillus licheniformis spores
por: Løvdal, Irene S, et al.
Publicado: (2012)

Acute β-N-Methylamino-L-alanine Toxicity in a Mouse Model
por: Al-Sammak, Maitham Ahmed, et al.
Publicado: (2015)

Na(+)-NQR Confers Aminoglycoside Resistance via the Regulation of l-Alanine Metabolism
por: Jiang, Ming, et al.
Publicado: (2020)

Biodistribution and racemization of gut-absorbed l/d-alanine in germ-free mice
por: Qiu, Tian (Autumn), et al.
Publicado: (2023)

Advances in the synthesis of β-alanine
por: Song, Peng, et al.
Publicado: (2023)

Development of a Novel Antimicrobial Screening System Targeting the Pyoverdine-Mediated Iron Acquisition System and Xenobiotic Efflux Pumps
por: Sato, Kazuki, et al.
Publicado: (2015)

Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis
por: Prosser, Gareth A., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ouf7ftdjudr8mg09noijjmhe7q