Cargando…

Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding

Background and study aims: Early video capsule endoscopy (VCE) may provide a high diagnostic yield and improve clinical outcomes in patients with overt obscure gastrointestinal bleeding (OGIB); however, there is no practical recommendation for the ideal timing of VCE application in overt OGIB. There...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Seung Han, Keum, Bora, Chun, Hoon Jai, Yoo, In Kyung, Lee, Jae Min, Lee, Jong Soo, Nam, Seung Joo, Choi, Hyuk Soon, Kim, Eun Sun, Seo, Yeon Seok, Jeen, Yoon Tae, Lee, Hong Sik, Um, Soon Ho, Kim, Chang Duck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Georg Thieme Verlag KG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554504/
https://www.ncbi.nlm.nih.gov/pubmed/26357679
http://dx.doi.org/10.1055/s-0034-1391852
_version_ 1782388069320622080
author Kim, Seung Han
Keum, Bora
Chun, Hoon Jai
Yoo, In Kyung
Lee, Jae Min
Lee, Jong Soo
Nam, Seung Joo
Choi, Hyuk Soon
Kim, Eun Sun
Seo, Yeon Seok
Jeen, Yoon Tae
Lee, Hong Sik
Um, Soon Ho
Kim, Chang Duck
author_facet Kim, Seung Han
Keum, Bora
Chun, Hoon Jai
Yoo, In Kyung
Lee, Jae Min
Lee, Jong Soo
Nam, Seung Joo
Choi, Hyuk Soon
Kim, Eun Sun
Seo, Yeon Seok
Jeen, Yoon Tae
Lee, Hong Sik
Um, Soon Ho
Kim, Chang Duck
author_sort Kim, Seung Han
collection PubMed
description Background and study aims: Early video capsule endoscopy (VCE) may provide a high diagnostic yield and improve clinical outcomes in patients with overt obscure gastrointestinal bleeding (OGIB); however, there is no practical recommendation for the ideal timing of VCE application in overt OGIB. Therefore, this study investigated the diagnostic yield and efficacy of VCE to assess overt OGIB with respect to the timing of application. Patients and methods: We retrospectively enrolled patients who had undergone VCE for overt OGIB between April 2004 and February 2014 at a tertiary referral academic center. We included hemodynamically stable patients who underwent VCE for overt OGIB after negative bidirectional endoscopy. We analyzed the diagnostic yield of VCE, therapeutic intervention rate, and length of hospital stay. Results: A total of 94 patients underwent VCE to assess overt OGIB. The diagnostic yields in the groups that underwent VCE < 48 h and > 48 h from the last overt OGIB were 66.7 % and 40.6 %, respectively (P = 0.019). Therapeutic intervention was performed in 26.7 % and 9.4 % of patients in the < 48-h and > 48-h groups, respectively (P = 0.028). The mean lengths of hospital stay in the < 48-h and > 48-h groups were 5 days (95 % confidence interval [CI], 4.8 – 7.7) and 7 days (95 %CI, 6.9 – 10.1), respectively (P = 0.039). Conclusions: Performing VCE within 2 days from the last overt OGIB results in a higher diagnostic yield, higher therapeutic intervention rate, and shorter hospital stay. Therefore, VCE application with a 48-h cutoff could improve the outcome of patients with overt OGIB.
format Online
Article
Text
id pubmed-4554504
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher © Georg Thieme Verlag KG
record_format MEDLINE/PubMed
spelling pubmed-45545042015-09-09 Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding Kim, Seung Han Keum, Bora Chun, Hoon Jai Yoo, In Kyung Lee, Jae Min Lee, Jong Soo Nam, Seung Joo Choi, Hyuk Soon Kim, Eun Sun Seo, Yeon Seok Jeen, Yoon Tae Lee, Hong Sik Um, Soon Ho Kim, Chang Duck Endosc Int Open Article Background and study aims: Early video capsule endoscopy (VCE) may provide a high diagnostic yield and improve clinical outcomes in patients with overt obscure gastrointestinal bleeding (OGIB); however, there is no practical recommendation for the ideal timing of VCE application in overt OGIB. Therefore, this study investigated the diagnostic yield and efficacy of VCE to assess overt OGIB with respect to the timing of application. Patients and methods: We retrospectively enrolled patients who had undergone VCE for overt OGIB between April 2004 and February 2014 at a tertiary referral academic center. We included hemodynamically stable patients who underwent VCE for overt OGIB after negative bidirectional endoscopy. We analyzed the diagnostic yield of VCE, therapeutic intervention rate, and length of hospital stay. Results: A total of 94 patients underwent VCE to assess overt OGIB. The diagnostic yields in the groups that underwent VCE < 48 h and > 48 h from the last overt OGIB were 66.7 % and 40.6 %, respectively (P = 0.019). Therapeutic intervention was performed in 26.7 % and 9.4 % of patients in the < 48-h and > 48-h groups, respectively (P = 0.028). The mean lengths of hospital stay in the < 48-h and > 48-h groups were 5 days (95 % confidence interval [CI], 4.8 – 7.7) and 7 days (95 %CI, 6.9 – 10.1), respectively (P = 0.039). Conclusions: Performing VCE within 2 days from the last overt OGIB results in a higher diagnostic yield, higher therapeutic intervention rate, and shorter hospital stay. Therefore, VCE application with a 48-h cutoff could improve the outcome of patients with overt OGIB. © Georg Thieme Verlag KG 2015-08 2015-05-05 /pmc/articles/PMC4554504/ /pubmed/26357679 http://dx.doi.org/10.1055/s-0034-1391852 Text en © Thieme Medical Publishers
spellingShingle Article
Kim, Seung Han
Keum, Bora
Chun, Hoon Jai
Yoo, In Kyung
Lee, Jae Min
Lee, Jong Soo
Nam, Seung Joo
Choi, Hyuk Soon
Kim, Eun Sun
Seo, Yeon Seok
Jeen, Yoon Tae
Lee, Hong Sik
Um, Soon Ho
Kim, Chang Duck
Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding
title Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding
title_full Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding
title_fullStr Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding
title_full_unstemmed Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding
title_short Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding
title_sort efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554504/
https://www.ncbi.nlm.nih.gov/pubmed/26357679
http://dx.doi.org/10.1055/s-0034-1391852
work_keys_str_mv AT kimseunghan efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT keumbora efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT chunhoonjai efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT yooinkyung efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT leejaemin efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT leejongsoo efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT namseungjoo efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT choihyuksoon efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT kimeunsun efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT seoyeonseok efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT jeenyoontae efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT leehongsik efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT umsoonho efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding
AT kimchangduck efficacyandimplicationsofa48hcutoffforvideocapsuleendoscopyapplicationinovertobscuregastrointestinalbleeding