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Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding
Background and study aims: Early video capsule endoscopy (VCE) may provide a high diagnostic yield and improve clinical outcomes in patients with overt obscure gastrointestinal bleeding (OGIB); however, there is no practical recommendation for the ideal timing of VCE application in overt OGIB. There...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
© Georg Thieme Verlag KG
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554504/ https://www.ncbi.nlm.nih.gov/pubmed/26357679 http://dx.doi.org/10.1055/s-0034-1391852 |
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author | Kim, Seung Han Keum, Bora Chun, Hoon Jai Yoo, In Kyung Lee, Jae Min Lee, Jong Soo Nam, Seung Joo Choi, Hyuk Soon Kim, Eun Sun Seo, Yeon Seok Jeen, Yoon Tae Lee, Hong Sik Um, Soon Ho Kim, Chang Duck |
author_facet | Kim, Seung Han Keum, Bora Chun, Hoon Jai Yoo, In Kyung Lee, Jae Min Lee, Jong Soo Nam, Seung Joo Choi, Hyuk Soon Kim, Eun Sun Seo, Yeon Seok Jeen, Yoon Tae Lee, Hong Sik Um, Soon Ho Kim, Chang Duck |
author_sort | Kim, Seung Han |
collection | PubMed |
description | Background and study aims: Early video capsule endoscopy (VCE) may provide a high diagnostic yield and improve clinical outcomes in patients with overt obscure gastrointestinal bleeding (OGIB); however, there is no practical recommendation for the ideal timing of VCE application in overt OGIB. Therefore, this study investigated the diagnostic yield and efficacy of VCE to assess overt OGIB with respect to the timing of application. Patients and methods: We retrospectively enrolled patients who had undergone VCE for overt OGIB between April 2004 and February 2014 at a tertiary referral academic center. We included hemodynamically stable patients who underwent VCE for overt OGIB after negative bidirectional endoscopy. We analyzed the diagnostic yield of VCE, therapeutic intervention rate, and length of hospital stay. Results: A total of 94 patients underwent VCE to assess overt OGIB. The diagnostic yields in the groups that underwent VCE < 48 h and > 48 h from the last overt OGIB were 66.7 % and 40.6 %, respectively (P = 0.019). Therapeutic intervention was performed in 26.7 % and 9.4 % of patients in the < 48-h and > 48-h groups, respectively (P = 0.028). The mean lengths of hospital stay in the < 48-h and > 48-h groups were 5 days (95 % confidence interval [CI], 4.8 – 7.7) and 7 days (95 %CI, 6.9 – 10.1), respectively (P = 0.039). Conclusions: Performing VCE within 2 days from the last overt OGIB results in a higher diagnostic yield, higher therapeutic intervention rate, and shorter hospital stay. Therefore, VCE application with a 48-h cutoff could improve the outcome of patients with overt OGIB. |
format | Online Article Text |
id | pubmed-4554504 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | © Georg Thieme Verlag KG |
record_format | MEDLINE/PubMed |
spelling | pubmed-45545042015-09-09 Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding Kim, Seung Han Keum, Bora Chun, Hoon Jai Yoo, In Kyung Lee, Jae Min Lee, Jong Soo Nam, Seung Joo Choi, Hyuk Soon Kim, Eun Sun Seo, Yeon Seok Jeen, Yoon Tae Lee, Hong Sik Um, Soon Ho Kim, Chang Duck Endosc Int Open Article Background and study aims: Early video capsule endoscopy (VCE) may provide a high diagnostic yield and improve clinical outcomes in patients with overt obscure gastrointestinal bleeding (OGIB); however, there is no practical recommendation for the ideal timing of VCE application in overt OGIB. Therefore, this study investigated the diagnostic yield and efficacy of VCE to assess overt OGIB with respect to the timing of application. Patients and methods: We retrospectively enrolled patients who had undergone VCE for overt OGIB between April 2004 and February 2014 at a tertiary referral academic center. We included hemodynamically stable patients who underwent VCE for overt OGIB after negative bidirectional endoscopy. We analyzed the diagnostic yield of VCE, therapeutic intervention rate, and length of hospital stay. Results: A total of 94 patients underwent VCE to assess overt OGIB. The diagnostic yields in the groups that underwent VCE < 48 h and > 48 h from the last overt OGIB were 66.7 % and 40.6 %, respectively (P = 0.019). Therapeutic intervention was performed in 26.7 % and 9.4 % of patients in the < 48-h and > 48-h groups, respectively (P = 0.028). The mean lengths of hospital stay in the < 48-h and > 48-h groups were 5 days (95 % confidence interval [CI], 4.8 – 7.7) and 7 days (95 %CI, 6.9 – 10.1), respectively (P = 0.039). Conclusions: Performing VCE within 2 days from the last overt OGIB results in a higher diagnostic yield, higher therapeutic intervention rate, and shorter hospital stay. Therefore, VCE application with a 48-h cutoff could improve the outcome of patients with overt OGIB. © Georg Thieme Verlag KG 2015-08 2015-05-05 /pmc/articles/PMC4554504/ /pubmed/26357679 http://dx.doi.org/10.1055/s-0034-1391852 Text en © Thieme Medical Publishers |
spellingShingle | Article Kim, Seung Han Keum, Bora Chun, Hoon Jai Yoo, In Kyung Lee, Jae Min Lee, Jong Soo Nam, Seung Joo Choi, Hyuk Soon Kim, Eun Sun Seo, Yeon Seok Jeen, Yoon Tae Lee, Hong Sik Um, Soon Ho Kim, Chang Duck Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding |
title | Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding |
title_full | Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding |
title_fullStr | Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding |
title_full_unstemmed | Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding |
title_short | Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding |
title_sort | efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure gastrointestinal bleeding |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554504/ https://www.ncbi.nlm.nih.gov/pubmed/26357679 http://dx.doi.org/10.1055/s-0034-1391852 |
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