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The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma

Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumour in humans and is highly resistant to current treatment modalities. We have explored the combined treatment of the endoplasmic reticulum (ER) stress-inducing agent 2,5-dimethyl-celecoxib (DMC) and TNF-related apoptosis-induci...

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Detalles Bibliográficos
Autores principales:	van Roosmalen, Ingrid A M, Reis, Carlos R, Setroikromo, Rita, Yuvaraj, Saravanan, Joseph, Justin V, Tepper, Pieter G, Kruyt, Frank A E, Quax, Wim J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554544/ https://www.ncbi.nlm.nih.gov/pubmed/26331107 http://dx.doi.org/10.1186/2193-1801-3-495

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