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MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation

In developing male germ cells, prospermatogonia, two Piwi proteins, MILI and MIWI2, use Piwi-interacting RNA (piRNA) guides to repress transposable element (TE) expression and ensure genome stability and proper gametogenesis. In addition to their roles in post-transcriptional TE repression, both pro...

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Detalles Bibliográficos
Autores principales:	Manakov, Sergei A., Pezic, Dubravka, Marinov, Georgi K., Pastor, William A., Sachidanandam, Ravi, Aravin, Alexei A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554733/ https://www.ncbi.nlm.nih.gov/pubmed/26279574 http://dx.doi.org/10.1016/j.celrep.2015.07.036

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