Cargando…

MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation

In developing male germ cells, prospermatogonia, two Piwi proteins, MILI and MIWI2, use Piwi-interacting RNA (piRNA) guides to repress transposable element (TE) expression and ensure genome stability and proper gametogenesis. In addition to their roles in post-transcriptional TE repression, both pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Manakov, Sergei A., Pezic, Dubravka, Marinov, Georgi K., Pastor, William A., Sachidanandam, Ravi, Aravin, Alexei A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554733/ https://www.ncbi.nlm.nih.gov/pubmed/26279574 http://dx.doi.org/10.1016/j.celrep.2015.07.036

Ejemplares similares

Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis
por: Vourekas, Anastassios, et al.
Publicado: (2012)

piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells
por: Pezic, Dubravka, et al.
Publicado: (2014)

Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis
por: Ding, Deqiang, et al.
Publicado: (2019)

Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing
por: Le Thomas, Adrien, et al.
Publicado: (2014)

A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming
por: Vasilauskaitė, Lina, et al.
Publicado: (2017)

Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes
por: Kabayama, Yuka, et al.
Publicado: (2017)

MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes
por: Zhang, Peng, et al.
Publicado: (2015)

Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex
por: Huang, Xiawei, et al.
Publicado: (2021)

To be or not to be a piRNA: genomic origin and processing of piRNAs
por: Le Thomas, Adrien, et al.
Publicado: (2014)

PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway
por: Yang, Zhaolin, et al.
Publicado: (2016)

The Cochaperone Shutdown Defines a Group of Biogenesis Factors Essential for All piRNA Populations in Drosophila
por: Olivieri, Daniel, et al.
Publicado: (2012)

Stellate Genes and the piRNA Pathway in Speciation and Reproductive Isolation of Drosophila melanogaster
por: Adashev, Vladimir E., et al.
Publicado: (2021)

piRNA-guided slicing of transposon transcripts enforces their transcriptional silencing via specifying the nuclear piRNA repertoire
por: Senti, Kirsten-André, et al.
Publicado: (2015)

Splicing-independent loading of TREX on nascent RNA is required for efficient expression of dual-strand piRNA clusters in Drosophila
por: Hur, Junho K., et al.
Publicado: (2016)

MIWI N-terminal RG motif promotes efficient pachytene piRNA production and spermatogenesis independent of LINE1 transposon silencing
por: Wei, Chao, et al.
Publicado: (2023)

Pervasive SUMOylation of heterochromatin and piRNA pathway proteins
por: Ninova, Maria, et al.
Publicado: (2023)

Vreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila
por: Zamparini, Andrea L., et al.
Publicado: (2011)

Distinct Roles of RNA Helicases MVH and TDRD9 in PIWI Slicing-Triggered Mammalian piRNA Biogenesis and Function
por: Wenda, Joanna M., et al.
Publicado: (2017)

Minotaur is critical for primary piRNA biogenesis
por: Vagin, Vasily V., et al.
Publicado: (2013)

piRNA silencing contributes to interspecies hybrid sterility and reproductive isolation in Drosophila melanogaster
por: Kotov, Alexei A, et al.
Publicado: (2019)

piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in D. melanogaster male germline
por: Chen, Peiwei, et al.
Publicado: (2021)

MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells
por: Kojima-Kita, Kanako, et al.
Publicado: (2021)

Cytoplasmic Compartmentalization of the Fetal piRNA Pathway in Mice
por: Aravin, Alexei A., et al.
Publicado: (2009)

The Biogenesis and Functions of piRNAs in Human Diseases
por: Wu, Xi, et al.
Publicado: (2020)

MORC1 represses transposable elements in the mouse male germline
por: Pastor, William A., et al.
Publicado: (2014)

Erratum: MORC1 represses transposable elements in the mouse male germline
por: Pastor, William A., et al.
Publicado: (2015)

Diversity of the piRNA pathway for nonself silencing: worm-specific piRNA biogenesis factors
por: Izumi, Natsuko, et al.
Publicado: (2014)

RDC complex executes a dynamic piRNA program during Drosophila spermatogenesis to safeguard male fertility
por: Chen, Peiwei, et al.
Publicado: (2021)

Computational Analysis of Mouse piRNA Sequence and Biogenesis
por: Betel, Doron, et al.
Publicado: (2007)

Fly piRNA biogenesis: tap dancing with Tej
por: Yang, Zhaolin, et al.
Publicado: (2014)

The MID-PIWI module of Piwi proteins specifies nucleotide- and strand-biases of piRNAs
por: Cora, Elisa, et al.
Publicado: (2014)

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis
por: Ipsaro, Jonathan J., et al.
Publicado: (2012)

Molecular basis for PICS-mediated piRNA biogenesis and cell division
por: Wang, Xiaoyang, et al.
Publicado: (2021)

T-hairpin structure found in the RNA element involved in piRNA biogenesis
por: Takase, Naomi, et al.
Publicado: (2022)

¿Para qué sirve la "Mili"? : funciones del servicio militar obligatorio en España /
por: Barroso Ribal, Cristino
Publicado: (1991)

Selectively Constrained RNA Editing Regulation Crosstalks with piRNA Biogenesis in Primates
por: Yang, Xin-Zhuang, et al.
Publicado: (2015)

The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells
por: Honda, Shozo, et al.
Publicado: (2017)

Role of piRNA biogenesis and its neuronal function in the development of neurodegenerative diseases
por: Sato, Kaoru, et al.
Publicado: (2023)

Daedalus and Gasz recruit Armitage to mitochondria, bringing piRNA precursors to the biogenesis machinery
por: Munafò, Marzia, et al.
Publicado: (2019)

Recruitment of Armitage and Yb to a transcript triggers its phased processing into primary piRNAs in Drosophila ovaries
por: Pandey, Radha Raman, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_kmno9lf93s2p5q6vs9fmukea7n