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Electrochemotherapy of tumors as in situ vaccination boosted by immunogene electrotransfer

Electroporation is a platform technology for drug and gene delivery. When applied to cell in vitro or tissues in vivo, it leads to an increase in membrane permeability for molecules which otherwise cannot enter the cell (e.g., siRNA, plasmid DNA, and some chemotherapeutic drugs). The therapeutic eff...

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Detalles Bibliográficos
Autores principales: Sersa, Gregor, Teissie, Justin, Cemazar, Maja, Signori, Emanuela, Kamensek, Urska, Marshall, Guillermo, Miklavcic, Damijan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554735/
https://www.ncbi.nlm.nih.gov/pubmed/26067277
http://dx.doi.org/10.1007/s00262-015-1724-2

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