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Stories and Challenges of Genome Wide Association Studies in Livestock — A Review

Undoubtedly livestock is one of the major contributors to the economy of any country. The economic value of livestock includes meat, dairy products, fiber, fertilizer etc. Understanding and identifying the associations of quantitative trait loci (QTL) with the economically important traits is believ...

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Autores principales: Sharma, Aditi, Lee, Jun Seop, Dang, Chang Gwon, Sudrajad, Pita, Kim, Hyeong Cheol, Yeon, Seong Heum, Kang, Hee Seol, Lee, Seung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554843/
https://www.ncbi.nlm.nih.gov/pubmed/26194229
http://dx.doi.org/10.5713/ajas.14.0715
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author Sharma, Aditi
Lee, Jun Seop
Dang, Chang Gwon
Sudrajad, Pita
Kim, Hyeong Cheol
Yeon, Seong Heum
Kang, Hee Seol
Lee, Seung-Hwan
author_facet Sharma, Aditi
Lee, Jun Seop
Dang, Chang Gwon
Sudrajad, Pita
Kim, Hyeong Cheol
Yeon, Seong Heum
Kang, Hee Seol
Lee, Seung-Hwan
author_sort Sharma, Aditi
collection PubMed
description Undoubtedly livestock is one of the major contributors to the economy of any country. The economic value of livestock includes meat, dairy products, fiber, fertilizer etc. Understanding and identifying the associations of quantitative trait loci (QTL) with the economically important traits is believed to substantially benefit the livestock industry. The past two decades have seen a flurry of interest in mapping the QTL associated with traits of economic importance on the genome. With the availability of single nucleotide polymorphism chip of various densities it is possible to identify regions, QTL and genes on the genome that explain the association and its effect on the phenotype under consideration. Remarkable advancement has been seen in genome wide association studies (GWAS) since its inception till the present day. In this review we describe the progress and challenges of GWAS in various livestock species.
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spelling pubmed-45548432015-10-01 Stories and Challenges of Genome Wide Association Studies in Livestock — A Review Sharma, Aditi Lee, Jun Seop Dang, Chang Gwon Sudrajad, Pita Kim, Hyeong Cheol Yeon, Seong Heum Kang, Hee Seol Lee, Seung-Hwan Asian-Australas J Anim Sci Article Undoubtedly livestock is one of the major contributors to the economy of any country. The economic value of livestock includes meat, dairy products, fiber, fertilizer etc. Understanding and identifying the associations of quantitative trait loci (QTL) with the economically important traits is believed to substantially benefit the livestock industry. The past two decades have seen a flurry of interest in mapping the QTL associated with traits of economic importance on the genome. With the availability of single nucleotide polymorphism chip of various densities it is possible to identify regions, QTL and genes on the genome that explain the association and its effect on the phenotype under consideration. Remarkable advancement has been seen in genome wide association studies (GWAS) since its inception till the present day. In this review we describe the progress and challenges of GWAS in various livestock species. Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2015-10 /pmc/articles/PMC4554843/ /pubmed/26194229 http://dx.doi.org/10.5713/ajas.14.0715 Text en Copyright © 2015 by Asian-Australasian Journal of Animal Sciences
spellingShingle Article
Sharma, Aditi
Lee, Jun Seop
Dang, Chang Gwon
Sudrajad, Pita
Kim, Hyeong Cheol
Yeon, Seong Heum
Kang, Hee Seol
Lee, Seung-Hwan
Stories and Challenges of Genome Wide Association Studies in Livestock — A Review
title Stories and Challenges of Genome Wide Association Studies in Livestock — A Review
title_full Stories and Challenges of Genome Wide Association Studies in Livestock — A Review
title_fullStr Stories and Challenges of Genome Wide Association Studies in Livestock — A Review
title_full_unstemmed Stories and Challenges of Genome Wide Association Studies in Livestock — A Review
title_short Stories and Challenges of Genome Wide Association Studies in Livestock — A Review
title_sort stories and challenges of genome wide association studies in livestock — a review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554843/
https://www.ncbi.nlm.nih.gov/pubmed/26194229
http://dx.doi.org/10.5713/ajas.14.0715
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