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Ultrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesis

The key role of mitochondria in patients affected by amyotrophic lateral sclerosis (ALS) is well documented by electron microscopy studies of motor neurons within spinal cord and brainstem. Nonetheless, recent studies challenged the role of mitochondria placed within the cell body of motor neuron. I...

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Detalles Bibliográficos
Autores principales:	Ruffoli, Riccardo, Bartalucci, Alessia, Frati, Alessandro, Fornai, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555074/ https://www.ncbi.nlm.nih.gov/pubmed/26388731 http://dx.doi.org/10.3389/fncel.2015.00341

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