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Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice

Patients with inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis, often suffer drug intolerance. This resistance can be divided into intrinsic resistance and acquired resistance. Although there is agreement on acquired resistance, studies regarding intrinsic resistance hav...

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Detalles Bibliográficos
Autores principales: Liu, Jiali, Zhou, Fang, Chen, Qianying, Kang, An, Lu, Meng, Liu, Wenyue, Zang, Xiaojie, Wang, Guangji, Zhang, Jingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555107/
https://www.ncbi.nlm.nih.gov/pubmed/26324318
http://dx.doi.org/10.1038/srep13558