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Physicochemical and biological characterization of chitosan-microRNA nanocomplexes for gene delivery to MCF-7 breast cancer cells

Cancer gene therapy requires the design of non-viral vectors that carry genetic material and selectively deliver it with minimal toxicity. Non-viral vectors based on cationic natural polymers can form electrostatic complexes with negatively-charged polynucleotides such as microRNAs (miRNAs). Here we...

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Detalles Bibliográficos
Autores principales:	Santos-Carballal, B., Aaldering, L. J., Ritzefeld, M., Pereira, S., Sewald, N., Moerschbacher, B. M., Götte, M., Goycoolea, F. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555168/ https://www.ncbi.nlm.nih.gov/pubmed/26324407 http://dx.doi.org/10.1038/srep13567

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