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Increased expression of surface CD44 in hypoxia-DCs skews helper T cells toward a Th2 polarization

A low partial oxygen pressure (hypoxia) occurs in many pathological environments, such as solid tumors and inflammatory lesions. Understanding the cellular response to hypoxic stress has broad implications for human diseases. As we previously reported, hypoxia significantly altered dendritic cells (...

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Detalles Bibliográficos
Autores principales: Yang, Meixiang, Liu, Yanguo, Ren, Guangwen, Shao, Qianqian, Gao, Wenjuan, Sun, Jintang, Wang, Huayang, Ji, Chunyan, Li, Xingang, Zhang, Yun, Qu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555176/
https://www.ncbi.nlm.nih.gov/pubmed/26323509
http://dx.doi.org/10.1038/srep13674