Cargando…

Rapid Identification of Chemoresistance Mechanisms Using Yeast DNA Mismatch Repair Mutants

Resistance to cancer therapy is a major obstacle in the long-term treatment of cancer. A greater understanding of drug resistance mechanisms will ultimately lead to the development of effective therapeutic strategies to prevent resistance from occurring. Here, we exploit the mutator phenotype of mis...

Descripción completa

Detalles Bibliográficos
Autores principales: Ojini, Irene, Gammie, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555229/
https://www.ncbi.nlm.nih.gov/pubmed/26199284
http://dx.doi.org/10.1534/g3.115.020560