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Rapid Identification of Chemoresistance Mechanisms Using Yeast DNA Mismatch Repair Mutants
Resistance to cancer therapy is a major obstacle in the long-term treatment of cancer. A greater understanding of drug resistance mechanisms will ultimately lead to the development of effective therapeutic strategies to prevent resistance from occurring. Here, we exploit the mutator phenotype of mis...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555229/ https://www.ncbi.nlm.nih.gov/pubmed/26199284 http://dx.doi.org/10.1534/g3.115.020560 |