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The effects of Tmc1 Beethoven mutation on mechanotransducer channel function in cochlear hair cells
Sound stimuli are converted into electrical signals via gating of mechano-electrical transducer (MT) channels in the hair cell stereociliary bundle. The molecular composition of the MT channel is still not fully established, although transmembrane channel–like protein isoform 1 (TMC1) may be one com...
Autores principales: | Beurg, Maryline, Goldring, Adam C., Fettiplace, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555472/ https://www.ncbi.nlm.nih.gov/pubmed/26324676 http://dx.doi.org/10.1085/jgp.201511458 |
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