Concentrating on the mitotic spindle

In eukaryotes, the microtubule-based spindle drives chromosome segregation. In this issue, Schweizer et al. (2015; J. Cell Biol. http://dx.doi.org/10.1083/jcb.201506107) find that the spindle area is demarcated by a semipermeable organelle barrier. Molecular crowding, which is microtubule independen...

Descripción completa

Detalles Bibliográficos
Autores principales: Maddox, Paul S., Ladouceur, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555814/
https://www.ncbi.nlm.nih.gov/pubmed/26323687
http://dx.doi.org/10.1083/jcb.201508007
_version_ 1782388254371217408
author Maddox, Paul S.
Ladouceur, Anne-Marie
author_facet Maddox, Paul S.
Ladouceur, Anne-Marie
author_sort Maddox, Paul S.
collection PubMed
description In eukaryotes, the microtubule-based spindle drives chromosome segregation. In this issue, Schweizer et al. (2015; J. Cell Biol. http://dx.doi.org/10.1083/jcb.201506107) find that the spindle area is demarcated by a semipermeable organelle barrier. Molecular crowding, which is microtubule independent, causes the enrichment and/or retention of crucial factors in the spindle region. Their results add an important new feature to the models of how this structure assembles and is regulated.
format Online
Article
Text
id pubmed-4555814
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-45558142016-02-29 Concentrating on the mitotic spindle Maddox, Paul S. Ladouceur, Anne-Marie J Cell Biol Reviews In eukaryotes, the microtubule-based spindle drives chromosome segregation. In this issue, Schweizer et al. (2015; J. Cell Biol. http://dx.doi.org/10.1083/jcb.201506107) find that the spindle area is demarcated by a semipermeable organelle barrier. Molecular crowding, which is microtubule independent, causes the enrichment and/or retention of crucial factors in the spindle region. Their results add an important new feature to the models of how this structure assembles and is regulated. The Rockefeller University Press 2015-08-31 /pmc/articles/PMC4555814/ /pubmed/26323687 http://dx.doi.org/10.1083/jcb.201508007 Text en © 2015 Maddox and Ladouceur This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Maddox, Paul S.
Ladouceur, Anne-Marie
Concentrating on the mitotic spindle
title Concentrating on the mitotic spindle
title_full Concentrating on the mitotic spindle
title_fullStr Concentrating on the mitotic spindle
title_full_unstemmed Concentrating on the mitotic spindle
title_short Concentrating on the mitotic spindle
title_sort concentrating on the mitotic spindle
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555814/
https://www.ncbi.nlm.nih.gov/pubmed/26323687
http://dx.doi.org/10.1083/jcb.201508007
work_keys_str_mv AT maddoxpauls concentratingonthemitoticspindle
AT ladouceurannemarie concentratingonthemitoticspindle

Ejemplares similares