Cargando…
Usp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis
During the G2 to M phase transition, a portion of mitotic regulator Plk1 localizes to the kinetochores and regulates the initiation of kinetochore–microtubule attachments for proper chromosome alignment. Once kinetochore–microtubule attachment is achieved, this portion of Plk1 is removed from the ki...
Autores principales: | Zhuo, Xiaolong, Guo, Xiao, Zhang, Xiaoyan, Jing, Guihua, Wang, Yao, Chen, Qiang, Jiang, Qing, Liu, Junjun, Zhang, Chuanmao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555819/ https://www.ncbi.nlm.nih.gov/pubmed/26323689 http://dx.doi.org/10.1083/jcb.201502044 |
Ejemplares similares
-
USP7 is a novel Deubiquitinase sustaining PLK1 protein stability and regulating chromosome alignment in mitosis
por: Peng, Yuchong, et al.
Publicado: (2019) -
Recent Progress on the Localization of PLK1 to the Kinetochore and Its Role in Mitosis
por: Kim, Taekyung
Publicado: (2022) -
Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1
por: Ehlén, Åsa, et al.
Publicado: (2020) -
Regulation of NDR1 activity by PLK1 ensures proper spindle orientation in mitosis
por: Yan, Maomao, et al.
Publicado: (2015) -
BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis
por: Singh, Priyanka, et al.
Publicado: (2021)