Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1

During development, netrin-1 is both an attractive and repulsive axon guidance cue and mediates its attractive function through the receptor Deleted in Colorectal Cancer (DCC). The activation of Rho guanosine triphosphatases within the extending growth cone facilitates the dynamic reorganization of...

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Detalles Bibliográficos
Autores principales: DeGeer, Jonathan, Kaplan, Andrew, Mattar, Pierre, Morabito, Morgane, Stochaj, Ursula, Kennedy, Timothy E., Debant, Anne, Cayouette, Michel, Fournier, Alyson E., Lamarche-Vane, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555821/
https://www.ncbi.nlm.nih.gov/pubmed/26323693
http://dx.doi.org/10.1083/jcb.201505084

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