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A profile of human immunodeficiency virus seroconcordant/serodiscordant couples

INTRODUCTION: Heterosexual route is the most common mode of human immunodeficiency virus (HIV) transmission among married couples in India. The aim of the study was to determine HIV seroconcordance and serodiscordance among couples when one of the partners is HIV positive. MATERIALS AND METHODS: A r...

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Autores principales: Marfatia, Yogesh S., Shinojia, Maulik A., Patel, Dimpal, Pandya, Ipsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555902/
https://www.ncbi.nlm.nih.gov/pubmed/26392657
http://dx.doi.org/10.4103/2589-0557.156731
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author Marfatia, Yogesh S.
Shinojia, Maulik A.
Patel, Dimpal
Pandya, Ipsa
author_facet Marfatia, Yogesh S.
Shinojia, Maulik A.
Patel, Dimpal
Pandya, Ipsa
author_sort Marfatia, Yogesh S.
collection PubMed
description INTRODUCTION: Heterosexual route is the most common mode of human immunodeficiency virus (HIV) transmission among married couples in India. The aim of the study was to determine HIV seroconcordance and serodiscordance among couples when one of the partners is HIV positive. MATERIALS AND METHODS: A retrospective study which included HIV positive married cohabiting cases was carried out at the Department of Skin-VD, Medical College, Baroda. Detailed history of high-risk sexual behavior, blood transfusion (BT) and sexually transmitted infections (STIs) was taken. All the cases were examined for the presence of STIs and all males were examined for circumcision. The spouses of these cases were tested for HIV to know the seroconcordance/serodiscordance. RESULTS: A total of 66 HIV positive cases were studied which included 34 males and 32 females. Forty-five cases had seropositive spouses that consisted of 20 out of 34 HIV positive males and 25 out of 32 HIV positive females. History of STI was present in 13 cases. History of BT in one of the spouses was present in 15 of 45 seroconcordant couples while in 6 out of 21 serodiscordant couples. Among 34 HIV positive males, circumcision was present in 8 cases out of which 6 were serodiscordant. DISCUSSION: About 68% concordance suggests continued intramarital transmission probably due to lack of spousal communication and late testing. In cases having transfusion transmitted HIV, seroconcordance rate was found to be high. Such cases are usually asymptomatic and hence tested late but continue to transmit HIV by unprotected sexual activity.
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spelling pubmed-45559022015-09-21 A profile of human immunodeficiency virus seroconcordant/serodiscordant couples Marfatia, Yogesh S. Shinojia, Maulik A. Patel, Dimpal Pandya, Ipsa Indian J Sex Transm Dis AIDS Study Report INTRODUCTION: Heterosexual route is the most common mode of human immunodeficiency virus (HIV) transmission among married couples in India. The aim of the study was to determine HIV seroconcordance and serodiscordance among couples when one of the partners is HIV positive. MATERIALS AND METHODS: A retrospective study which included HIV positive married cohabiting cases was carried out at the Department of Skin-VD, Medical College, Baroda. Detailed history of high-risk sexual behavior, blood transfusion (BT) and sexually transmitted infections (STIs) was taken. All the cases were examined for the presence of STIs and all males were examined for circumcision. The spouses of these cases were tested for HIV to know the seroconcordance/serodiscordance. RESULTS: A total of 66 HIV positive cases were studied which included 34 males and 32 females. Forty-five cases had seropositive spouses that consisted of 20 out of 34 HIV positive males and 25 out of 32 HIV positive females. History of STI was present in 13 cases. History of BT in one of the spouses was present in 15 of 45 seroconcordant couples while in 6 out of 21 serodiscordant couples. Among 34 HIV positive males, circumcision was present in 8 cases out of which 6 were serodiscordant. DISCUSSION: About 68% concordance suggests continued intramarital transmission probably due to lack of spousal communication and late testing. In cases having transfusion transmitted HIV, seroconcordance rate was found to be high. Such cases are usually asymptomatic and hence tested late but continue to transmit HIV by unprotected sexual activity. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4555902/ /pubmed/26392657 http://dx.doi.org/10.4103/2589-0557.156731 Text en Copyright: © Indian Journal of Sexually Transmitted Diseases and AIDS http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Study Report
Marfatia, Yogesh S.
Shinojia, Maulik A.
Patel, Dimpal
Pandya, Ipsa
A profile of human immunodeficiency virus seroconcordant/serodiscordant couples
title A profile of human immunodeficiency virus seroconcordant/serodiscordant couples
title_full A profile of human immunodeficiency virus seroconcordant/serodiscordant couples
title_fullStr A profile of human immunodeficiency virus seroconcordant/serodiscordant couples
title_full_unstemmed A profile of human immunodeficiency virus seroconcordant/serodiscordant couples
title_short A profile of human immunodeficiency virus seroconcordant/serodiscordant couples
title_sort profile of human immunodeficiency virus seroconcordant/serodiscordant couples
topic Study Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555902/
https://www.ncbi.nlm.nih.gov/pubmed/26392657
http://dx.doi.org/10.4103/2589-0557.156731
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