Whole-genome sequencing provides new insights into the clonal architecture of Barrett’s esophagus and esophageal adenocarcinoma

The molecular genetic relationship between esophageal adenocarcinoma (EAC) and its precursor lesion, Barrett’s esophagus, is poorly understood. Using whole-genome sequencing on 23 paired Barrett’s esophagus and EAC samples, together with one in-depth Barrett’s esophagus case-study sampled over time...

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Detalles Bibliográficos
Autores principales: Ross-Innes, Caryn S., Becq, Jennifer, Warren, Andrew, Cheetham, R. Keira, Northen, Helen, O’Donovan, Maria, Malhotra, Shalini, di Pietro, Massimiliano, Ivakhno, Sergii, He, Miao, Weaver, Jamie M.J., Lynch, Andy G., Kingsbury, Zoya, Ross, Mark, Humphray, Sean, Bentley, David, Fitzgerald, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556068/
https://www.ncbi.nlm.nih.gov/pubmed/26192915
http://dx.doi.org/10.1038/ng.3357

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