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Paraquat Induces Apoptosis through a Mitochondria-Dependent Pathway in RAW264.7 Cells

Paraquat dichloride (N,N-dimethyl-4-4′-bipiridinium, PQ) is an extremely toxic chemical that is widely used in herbicides. PQ generates reactive oxygen species (ROS) and causes multiple organ failure. In particular, PQ has been reported to be an immunotoxic agrochemical compound. PQ was shown to dec...

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Detalles Bibliográficos
Autores principales:	Jang, Yeo Jin, Won, Jong Hoon, Back, Moon Jung, Fu, Zhicheng, Jang, Ji Min, Ha, Hae Chan, Hong, SeungBeom, Chang, Minsun, Kim, Dae Kyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556199/ https://www.ncbi.nlm.nih.gov/pubmed/26336579 http://dx.doi.org/10.4062/biomolther.2015.075

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