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Measurement of Human Cytochrome P450 Enzyme Induction Based on Mesalazine and Mosapride Citrate Treatments Using a Luminescent Assay

Drug metabolism mostly occurs in the liver. Cytochrome P450 (CYP) is a drug-metabolizing enzyme that is responsible for many important drug metabolism reactions. Recently, the US FDA and EU EMA have suggested that CYP enzyme induction can be measured by both enzymatic activity and mRNA expression. H...

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Detalles Bibliográficos
Autores principales:	Kim, Young-Hoon, Bae, Young-Ji, Kim, Hyung Soo, Cha, Hey-Jin, Yun, Jae-Suk, Shin, Ji-Soon, Seong, Won-Keun, Lee, Yong-Moon, Han, Kyoung-Moon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556210/ https://www.ncbi.nlm.nih.gov/pubmed/26336590 http://dx.doi.org/10.4062/biomolther.2015.041

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