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Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by neutrophil articular infiltration, joint pain and the progressive destruction of cartilage and bone. IL-22 is a key effector molecule that plays a critical role in autoimmune diseases. However, the function of I...

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Detalles Bibliográficos
Autores principales: Pinto, Larissa G., Talbot, Jhimmy, Peres, Raphael S., Franca, Rafael F., Ferreira, Sérgio H., Ryffel, Bernhard, Aves-Filho, José Carlos F., Figueiredo, Florêncio, Cunha, Thiago M., Cunha, Fernando Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556214/
https://www.ncbi.nlm.nih.gov/pubmed/26330334
http://dx.doi.org/10.1186/s13075-015-0759-2