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Long Term Liver Engraftment of Functional Hepatocytes Obtained from Germline Cell-Derived Pluripotent Stem Cells
One of the major hurdles in liver gene and cell therapy is availability of ex vivo-expanded hepatocytes. Pluripotent stem cells are an attractive alternative. Here, we show that hepatocyte precursors can be isolated from male germline cell-derived pluripotent stem cells (GPSCs) using the hepatoblast...
Autores principales: | Fagoonee, Sharmila, Famulari, Elvira Smeralda, Silengo, Lorenzo, Tolosano, Emanuela, Altruda, Fiorella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556379/ https://www.ncbi.nlm.nih.gov/pubmed/26323094 http://dx.doi.org/10.1371/journal.pone.0136762 |
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