Exploiting single-molecule transcript sequencing for eukaryotic gene prediction

We develop a method to predict and validate gene models using PacBio single-molecule, real-time (SMRT) cDNA reads. Ninety-eight percent of full-insert SMRT reads span complete open reading frames. Gene model validation using SMRT reads is developed as automated process. Optimized training and predic...

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Detalles Bibliográficos
Autores principales: Minoche, André E., Dohm, Juliane C., Schneider, Jessica, Holtgräwe, Daniela, Viehöver, Prisca, Montfort, Magda, Rosleff Sörensen, Thomas, Weisshaar, Bernd, Himmelbauer, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556409/
https://www.ncbi.nlm.nih.gov/pubmed/26328666
http://dx.doi.org/10.1186/s13059-015-0729-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556409/
https://www.ncbi.nlm.nih.gov/pubmed/26328666
http://dx.doi.org/10.1186/s13059-015-0729-7

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