Oxygen - a limiting factor for brain recovery

Effective brain metabolism is highly dependent on a narrow therapeutic window of oxygen. In major insults to the brain (e.g., intracerebral hemorrhage), a slight decrease in oxygen supply, as occurs in a hypobaric environment at high altitude, has devastating effects on the injured brain tissue. Con...

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Detalles Bibliográficos
Autores principales: Hadanny, Amir, Efrati, Shai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556415/
https://www.ncbi.nlm.nih.gov/pubmed/26329929
http://dx.doi.org/10.1186/s13054-015-1034-2
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author Hadanny, Amir
Efrati, Shai
author_facet Hadanny, Amir
Efrati, Shai
author_sort Hadanny, Amir
collection PubMed
description Effective brain metabolism is highly dependent on a narrow therapeutic window of oxygen. In major insults to the brain (e.g., intracerebral hemorrhage), a slight decrease in oxygen supply, as occurs in a hypobaric environment at high altitude, has devastating effects on the injured brain tissue. Conversely, increasing brain oxygenation, by the use of hyperbaric oxygen therapy, can improve brain metabolism and its dependent regenerative processes.
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spelling pubmed-45564152015-09-02 Oxygen - a limiting factor for brain recovery Hadanny, Amir Efrati, Shai Crit Care Commentary Effective brain metabolism is highly dependent on a narrow therapeutic window of oxygen. In major insults to the brain (e.g., intracerebral hemorrhage), a slight decrease in oxygen supply, as occurs in a hypobaric environment at high altitude, has devastating effects on the injured brain tissue. Conversely, increasing brain oxygenation, by the use of hyperbaric oxygen therapy, can improve brain metabolism and its dependent regenerative processes. BioMed Central 2015-09-01 2015 /pmc/articles/PMC4556415/ /pubmed/26329929 http://dx.doi.org/10.1186/s13054-015-1034-2 Text en © Hadanny and Efrati. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
Hadanny, Amir
Efrati, Shai
Oxygen - a limiting factor for brain recovery
title Oxygen - a limiting factor for brain recovery
title_full Oxygen - a limiting factor for brain recovery
title_fullStr Oxygen - a limiting factor for brain recovery
title_full_unstemmed Oxygen - a limiting factor for brain recovery
title_short Oxygen - a limiting factor for brain recovery
title_sort oxygen - a limiting factor for brain recovery
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556415/
https://www.ncbi.nlm.nih.gov/pubmed/26329929
http://dx.doi.org/10.1186/s13054-015-1034-2
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