Exchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeutics

Mammalian exchange protein directly activated by cAMP isoform 1 (EPAC1), encoded by the RAPGEF3 gene, is one of the two-membered family of cAMP sensors that mediate the intracellular functions of cAMP by acting as guanine nucleotide exchange factors for the Ras-like Rap small GTPases. Extensive stud...

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Detalles Bibliográficos
Autores principales: Banerjee, Upasana, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556420/
https://www.ncbi.nlm.nih.gov/pubmed/26119090
http://dx.doi.org/10.1016/j.gene.2015.06.063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556420/
https://www.ncbi.nlm.nih.gov/pubmed/26119090
http://dx.doi.org/10.1016/j.gene.2015.06.063

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