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Genetics of Plasminogen Activator Inhibitor-1 (PAI-1) in a Ghanaian Population
Plasminogen activator inhibitor 1 (PAI-1), a major modulator of the fibrinolytic system, is an important factor in cardiovascular disease (CVD) susceptibility and severity. PAI-1 is highly heritable, but the few genes associated with it explain only a small portion of its variation. Studies of PAI-1...
Autores principales: | White, Marquitta J., Kodaman, Nuri M., Harder, Reed H., Asselbergs, Folkert W., Vaughan, Douglas E., Brown, Nancy J., Moore, Jason H., Williams, Scott M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556460/ https://www.ncbi.nlm.nih.gov/pubmed/26322636 http://dx.doi.org/10.1371/journal.pone.0136379 |
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