Are Quasi-Steady-State Approximated Models Suitable for Quantifying Intrinsic Noise Accurately?

Large gene regulatory networks (GRN) are often modeled with quasi-steady-state approximation (QSSA) to reduce the huge computational time required for intrinsic noise quantification using Gillespie stochastic simulation algorithm (SSA). However, the question still remains whether the stochastic QSSA...

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Detalles Bibliográficos
Autores principales: Sengupta, Dola, Kar, Sandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556639/
https://www.ncbi.nlm.nih.gov/pubmed/26327626
http://dx.doi.org/10.1371/journal.pone.0136668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556639/
https://www.ncbi.nlm.nih.gov/pubmed/26327626
http://dx.doi.org/10.1371/journal.pone.0136668

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