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High-Throughput siRNA Screening to Reveal GATA-2 Upstream Transcriptional Mechanisms in Hematopoietic Cells

Hematopoietic stem cells can self-renew and differentiate into all blood cell types. The transcription factor GATA-2 is expressed in both hematopoietic stem and progenitor cells and is essential for cell proliferation, survival, and differentiation. Recently, evidence from studies of aplastic anemia...

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Detalles Bibliográficos
Autores principales:	Saito, Yo, Fujiwara, Tohru, Ohashi, Keiichi, Okitsu, Yoko, Fukuhara, Noriko, Onishi, Yasushi, Ishizawa, Kenichi, Harigae, Hideo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556642/ https://www.ncbi.nlm.nih.gov/pubmed/26325290 http://dx.doi.org/10.1371/journal.pone.0137079

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