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The RNA Binding Protein Igf2bp1 Is Required for Zebrafish RGC Axon Outgrowth In Vivo

Attractive growth cone turning requires Igf2bp1-dependent local translation of β-actin mRNA in response to external cues in vitro. While in vivo studies have shown that Igf2bp1 is required for cell migration and axon terminal branching, a requirement for Igf2bp1 function during axon outgrowth has no...

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Detalles Bibliográficos
Autores principales: Gaynes, John A., Otsuna, Hideo, Campbell, Douglas S., Manfredi, John P., Levine, Edward M., Chien, Chi-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556669/
https://www.ncbi.nlm.nih.gov/pubmed/26325373
http://dx.doi.org/10.1371/journal.pone.0134751