In Vivo Silencing of A20 via TLR9-Mediated Targeted SiRNA Delivery Potentiates Antitumor Immune Response

A20 is an ubiquitin-editing enzyme that ensures the transient nature of inflammatory signaling pathways induced by cytokines like TNF-α and IL-1 or pathogens via Toll-like receptor (TLR) pathways. It has been identified as a negative regulator of dendritic cell (DC) maturation and attenuator of thei...

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Detalles Bibliográficos
Autores principales: Braun, Floriane C. M., van den Brandt, Jens, Thomas, Sören, Lange, Sandra, Schrank, Juliane, Gand, Claudia, Przybylski, Grzegorz K., Schmoeckel, Katrin, Bröker, Barbara M., Schmidt, Christian A., Grabarczyk, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556692/
https://www.ncbi.nlm.nih.gov/pubmed/26327508
http://dx.doi.org/10.1371/journal.pone.0135444

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