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Analysis of Nearly One Thousand Mammalian Mirtrons Reveals Novel Features of Dicer Substrates

Mirtrons are microRNA (miRNA) substrates that utilize the splicing machinery to bypass the necessity of Drosha cleavage for their biogenesis. Expanding our recent efforts for mammalian mirtron annotation, we use meta-analysis of aggregate datasets to identify ~500 novel mouse and human introns that...

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Detalles Bibliográficos
Autores principales: Wen, Jiayu, Ladewig, Erik, Shenker, Sol, Mohammed, Jaaved, Lai, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556696/
https://www.ncbi.nlm.nih.gov/pubmed/26325366
http://dx.doi.org/10.1371/journal.pcbi.1004441

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