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Analysis of Nearly One Thousand Mammalian Mirtrons Reveals Novel Features of Dicer Substrates
Mirtrons are microRNA (miRNA) substrates that utilize the splicing machinery to bypass the necessity of Drosha cleavage for their biogenesis. Expanding our recent efforts for mammalian mirtron annotation, we use meta-analysis of aggregate datasets to identify ~500 novel mouse and human introns that...
Autores principales: | Wen, Jiayu, Ladewig, Erik, Shenker, Sol, Mohammed, Jaaved, Lai, Eric C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556696/ https://www.ncbi.nlm.nih.gov/pubmed/26325366 http://dx.doi.org/10.1371/journal.pcbi.1004441 |
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