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A new high-resolution crystal structure of the Drosophila melanogaster angiotensin converting enzyme homologue, AnCE
Angiotensin converting enzyme (ACE) is a zinc-dependent dipeptidyl carboxypeptidase with an essential role in blood pressure homeostasis in mammals. ACE has long been targeted in the treatment of hypertension through ACE inhibitors, however current inhibitors are known to cause severe side effects....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556727/ https://www.ncbi.nlm.nih.gov/pubmed/26380810 http://dx.doi.org/10.1016/j.fob.2015.08.004 |