Activation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathway

Activation of the Notch3 cascade is involved in the development of pulmonary arterial hypertension by stimulating the proliferation of vascular smooth muscle cells. However, the detailed molecular mechanisms underlying this effect are still unclear. The present study aims to address this issue. We d...

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Detalles Bibliográficos
Autores principales: Song, Yang, Zhang, Yonghong, Jiang, Haoxiang, Zhu, Yanting, Liu, Lu, Feng, Wei, Yang, Lan, Wang, Yibin, Li, Manxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556730/
https://www.ncbi.nlm.nih.gov/pubmed/26380809
http://dx.doi.org/10.1016/j.fob.2015.08.007

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