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Complex I dysfunction underlies the glycolytic switch in pulmonary hypertensive smooth muscle cells

ATP is essential for cellular function and is usually produced through oxidative phosphorylation. However, mitochondrial dysfunction is now being recognized as an important contributing factor in the development cardiovascular diseases, such as pulmonary hypertension (PH). In PH there is a metabolic...

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Detalles Bibliográficos
Autores principales:	Rafikov, Ruslan, Sun, Xutong, Rafikova, Olga, Louise Meadows, Mary, Desai, Ankit A., Khalpey, Zain, Yuan, Jason X.-J., Fineman, Jeffrey R., Black, Stephen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556771/ https://www.ncbi.nlm.nih.gov/pubmed/26298201 http://dx.doi.org/10.1016/j.redox.2015.07.016

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