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Function of the CRISPR-Cas System of the Human Pathogen Clostridium difficile

Clostridium difficile is the cause of most frequently occurring nosocomial diarrhea worldwide. As an enteropathogen, C. difficile must be exposed to multiple exogenous genetic elements in bacteriophage-rich gut communities. CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRIS...

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Detalles Bibliográficos
Autores principales: Boudry, Pierre, Semenova, Ekaterina, Monot, Marc, Datsenko, Kirill A., Lopatina, Anna, Sekulovic, Ognjen, Ospina-Bedoya, Maicol, Fortier, Louis-Charles, Severinov, Konstantin, Dupuy, Bruno, Soutourina, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556805/
https://www.ncbi.nlm.nih.gov/pubmed/26330515
http://dx.doi.org/10.1128/mBio.01112-15