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Creation of non-human primate neurogenetic disease models by gene targeting and nuclear transfer
Genetically modified rhesus macaques are necessary because mouse models are not suitable for a number of important neurogenetic disorders; for example, Kallmann's syndrome, Lesch-Nyhan's disease and Ataxia-Telangiectasia. Mouse models may not be suitable because there may be no mouse ortho...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC455690/ https://www.ncbi.nlm.nih.gov/pubmed/15200671 http://dx.doi.org/10.1186/1477-7827-2-40 |