Cargando…
The Cellular Prion Protein: A Player in Immunological Quiescence
Despite intensive studies since the 1990s, the physiological role of the cellular prion protein (PrP(C)) remains elusive. Here, we present a novel concept suggesting that PrP(C) contributes to immunological quiescence in addition to cell protection. PrP(C) is highly expressed in diverse organs that...
Autores principales: | Bakkebø, Maren K., Mouillet-Richard, Sophie, Espenes, Arild, Goldmann, Wilfred, Tatzelt, Jörg, Tranulis, Michael A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557099/ https://www.ncbi.nlm.nih.gov/pubmed/26388873 http://dx.doi.org/10.3389/fimmu.2015.00450 |
Ejemplares similares
-
Goats without Prion Protein Display Enhanced Proinflammatory Pulmonary Signaling and Extracellular Matrix Remodeling upon Systemic Lipopolysaccharide Challenge
por: Salvesen, Øyvind, et al.
Publicado: (2017) -
Hematological shift in goat kids naturally devoid of prion protein
por: Reiten, Malin R., et al.
Publicado: (2015) -
Prion protein in myelin maintenance: what does the goat say?
por: Skedsmo, Fredrik S., et al.
Publicado: (2020) -
LPS-induced systemic inflammation reveals an immunomodulatory role for the prion protein at the blood-brain interface
por: Salvesen, Ø., et al.
Publicado: (2017) -
Loss of prion protein induces a primed state of type I interferon-responsive genes
por: Malachin, Giulia, et al.
Publicado: (2017)