NELL-1 in the treatment of osteoporotic bone loss

NELL-1 is a secreted, osteoinductive protein whose expression rheostatically controls skeletal ossification. Overexpression of NELL-1 results in craniosynostosis in humans and mice, whereas lack of Nell-1 expression is associated with skeletal undermineralization. Here we show that Nell-1-haploinsuf...

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Detalles Bibliográficos
Autores principales: James, Aaron W., Shen, Jia, Zhang, Xinli, Asatrian, Greg, Goyal, Raghav, Kwak, Jin H., Jiang, Lin, Bengs, Benjamin, Culiat, Cymbeline T., Turner, A. Simon, Seim III, Howard B., Wu, Benjamin M., Lyons, Karen, Adams, John S., Ting, Kang, Soo, Chia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557288/
https://www.ncbi.nlm.nih.gov/pubmed/26082355
http://dx.doi.org/10.1038/ncomms8362

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