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Hepatic insulin gene therapy prevents diabetic enteropathy in STZ-treated CD-1 mice

Depending on the population examined, from 6 to 83% of people with diabetes mellitus exhibit symptoms of altered gut motility, manifesting as dysphagia, reflux, early satiety, nausea, abdominal pain, diarrhea, or constipation. Hyperglycemia-induced cell loss within the enteric nervous system has bee...

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Detalles Bibliográficos
Autores principales: You, Shuo, Anitha, Mallappa, deSouza, Sean MD, Jia, Dingwu, Lu, Xianghua, Kozlowski, Miroslaw, Olson, Darin E, Srinivasan, Shanthi, Thulé, Peter M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557470/
https://www.ncbi.nlm.nih.gov/pubmed/26366426
http://dx.doi.org/10.1038/mtm.2015.28