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Resistance to multikinase inhibitor actions mediated by insulin like growth factor-1

BACKGROUND: Blood platelet numbers are correlated with growth and aggressiveness of several tumor types, including hepatocellular carcinoma (HCC). We previously found that platelet lysates (hPLs) both stimulated HCC cell growth and migration, and antagonized the growth-inhibitory and apoptotic effec...

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Detalles Bibliográficos
Autores principales: Lippolis, Catia, Refolo, Maria Grazia, D’Alessandro, Rosalba, Carella, Nicola, Messa, Caterina, Cavallini, Aldo, Carr, Brian Irving
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557596/
https://www.ncbi.nlm.nih.gov/pubmed/26329608
http://dx.doi.org/10.1186/s13046-015-0210-1