B cells regulate anti donor T cell reactivity in transplantation

The analyses of indirect T cell responses in patients with antibody-mediated renal transplant injury by Shiu et al. emphasize the complex contribution of B cells in alloimmunity. The data suggest at least three distinct but potentially overlapping consequences of T/B cell interactions: antigen prese...

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Detalles Bibliográficos
Autor principal: Valujskikh, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557620/
https://www.ncbi.nlm.nih.gov/pubmed/26323072
http://dx.doi.org/10.1038/ki.2015.171
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author Valujskikh, Anna
author_facet Valujskikh, Anna
author_sort Valujskikh, Anna
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description The analyses of indirect T cell responses in patients with antibody-mediated renal transplant injury by Shiu et al. emphasize the complex contribution of B cells in alloimmunity. The data suggest at least three distinct but potentially overlapping consequences of T/B cell interactions: antigen presentation by B cells, alloantibody production, and immune regulation. These multifaceted functions of B cells should be taken into consideration while developing diagnostic tools and therapeutic strategies.
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spelling pubmed-45576202016-03-01 B cells regulate anti donor T cell reactivity in transplantation Valujskikh, Anna Kidney Int Article The analyses of indirect T cell responses in patients with antibody-mediated renal transplant injury by Shiu et al. emphasize the complex contribution of B cells in alloimmunity. The data suggest at least three distinct but potentially overlapping consequences of T/B cell interactions: antigen presentation by B cells, alloantibody production, and immune regulation. These multifaceted functions of B cells should be taken into consideration while developing diagnostic tools and therapeutic strategies. 2015-09 /pmc/articles/PMC4557620/ /pubmed/26323072 http://dx.doi.org/10.1038/ki.2015.171 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Valujskikh, Anna
B cells regulate anti donor T cell reactivity in transplantation
title B cells regulate anti donor T cell reactivity in transplantation
title_full B cells regulate anti donor T cell reactivity in transplantation
title_fullStr B cells regulate anti donor T cell reactivity in transplantation
title_full_unstemmed B cells regulate anti donor T cell reactivity in transplantation
title_short B cells regulate anti donor T cell reactivity in transplantation
title_sort b cells regulate anti donor t cell reactivity in transplantation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557620/
https://www.ncbi.nlm.nih.gov/pubmed/26323072
http://dx.doi.org/10.1038/ki.2015.171
work_keys_str_mv AT valujskikhanna bcellsregulateantidonortcellreactivityintransplantation

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