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Large animal models of rare genetic disorders: sheep as phenotypically relevant models of human genetic disease
Animals that accurately model human disease are invaluable in medical research, allowing a critical understanding of disease mechanisms, and the opportunity to evaluate the effect of therapeutic compounds in pre-clinical studies. Many types of animal models are used world-wide, with the most common...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557632/ https://www.ncbi.nlm.nih.gov/pubmed/26329332 http://dx.doi.org/10.1186/s13023-015-0327-5 |