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Distinct CD4 T-cell effects on primary versus recall CD8 T-cell responses during viral encephalomyelitis
CD4 T-cell help is not a universal requirement for effective primary CD8 T cells but is essential to generate memory CD8 T cells capable of recall responses. This study examined how CD4 T cells affect primary and secondary anti-viral CD8 T-cell responses within the central nervous system (CNS) durin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557674/ https://www.ncbi.nlm.nih.gov/pubmed/25187405 http://dx.doi.org/10.1111/imm.12378 |