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CD8(+) T-cell recognition of a synthetic epitope formed by t-butyl modification

We set out to clone Bax-specific CD8(+) T cells from peripheral blood samples of patients with primary chronic lymphocytic leukaemia. A number of clones were generated using a Bax peptide pool and their T-cell epitope was mapped to two peptides sharing a common 9-amino-acid sequence (LLSYFGTPT), res...

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Detalles Bibliográficos
Autores principales: Reid, Reiss A, Redman, James E, Rizkallah, Pierre, Fegan, Chris, Pepper, Chris, Man, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557686/
https://www.ncbi.nlm.nih.gov/pubmed/25284607
http://dx.doi.org/10.1111/imm.12398

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