High Prevalence of inhA Promoter Mutations among Patients with Drug-Resistant Tuberculosis in KwaZulu-Natal, South Africa

BACKGROUND: Drug-resistant tuberculosis (TB) remains extremely difficult to treat because there are often few remaining active medications and limited diagnostic options to detect resistance. Resistance to isoniazid is typically caused by mutations in either katG or the inhA promoter. inhA mutations...

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Detalles Bibliográficos
Autores principales: Niehaus, Abraham J., Mlisana, Koleka, Gandhi, Neel R., Mathema, Barun, Brust, James C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557915/
https://www.ncbi.nlm.nih.gov/pubmed/26332235
http://dx.doi.org/10.1371/journal.pone.0135003

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