Similarities and Distinctions in Actions of Surface-Directed and Classic Androgen Receptor Antagonists

The androgen receptor (AR) surface-directed antagonist MJC13 inhibits AR function and proliferation of prostate cancer (PC) cells. These effects are related to arrest of an AR/chaperone complex in the cytoplasm. Here, we compared MJC13 and classic AR antagonists such as flutamide and bicalutamide. M...

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Detalles Bibliográficos
Autores principales: Suh, Ji Ho, Chattopadhyay, Arundhati, Sieglaff, Douglas H., Storer Samaniego, Cheryl, Cox, Marc B., Webb, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557941/
https://www.ncbi.nlm.nih.gov/pubmed/26332122
http://dx.doi.org/10.1371/journal.pone.0137103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557941/
https://www.ncbi.nlm.nih.gov/pubmed/26332122
http://dx.doi.org/10.1371/journal.pone.0137103

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